BDBM50207144 CHEMBL3940712::US9550741, IV-11

SMILES O=C(NCc1ccccc1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1

InChI Key InChIKey=HTHHKXUTDJTRGL-AFARHQOCSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207144   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM50207144(CHEMBL3940712 | US9550741, IV-11)
Affinity DataKi:  5.30nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM50207144(CHEMBL3940712 | US9550741, IV-11)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed